New genetic test improves artificial fertilization
in Nottingham now a child is born after his mother had already thirteen failed attempts with artificial insemination and three miscarriages. In the run-a genetic study of the eggs was carried out, but with the novel CGH method. Professor Fishel and his team studied the eggs of the 41-year-olds to chromosomal abnormalities that can reduce the likelihood of successful fertilization and pregnancy dramatically. According to Fishel
are in younger women up to 50% of the eggs "Chromosomally abnormal." Be women over 39 years up to 75%. The Oliver's mother was pregnant and now has brought a healthy child in the world can be understood according to Fishel contribute to why some women become pregnant.
The "Array comparative genomic hybridization (CGH) is checked whether the sets of chromosomes in the oocyte have also shared correctly. The egg cell contains initially namely the double set of chromosomes. So after fertilization not three sets of chromosomes in the egg cell are present, the egg divides , so that an egg is created with a single set of chromosomes and a so-called polar body, in which the "redundant" set of chromosomes is outsourced. The first polar body depend on the egg, but usually degraded by the body. In German, the method is therefore polar body (PKD).
In CGH, the polar body tested to see if it contains too many or too few chromosomes. it contains the correct number, correct the number of chromosomes in the egg cell and the Chances of successful fertilization and until the end of term pregnancy increase. When Oliver's mother, eight oocytes were studied - only two of which were chromosomally normal.
A similar method was U.S. researcher two years ago have great success in artificial insemination, then the diagnosis was much slower, so that the embryos had to be frozen and the mother could be used in the next cycle. The advantage of the new method lies in the speed reached by a meaningful result is
Fertility
Hiç yorum yok:
Yorum Gönder